|
Mutation Information
|
Mutation Site
|
I195M |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
S |
|
Relevant Drug
|
lamivudine (LAM) |
|
Country
|
Japan |
Literature Information
|
PubMed PMID
|
25817219
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2015 |
|
Journal
|
Journal of hepatology |
|
Title
|
Characterization of novel entecavir resistance mutations. |
|
Author
|
Hayashi S,Murakami S,Omagari K,Matsui T,Iio E,Isogawa M,Watanabe T,Karino Y,Tanaka Y |
|
Evidence
|
Moreover, one of the LAM resistance mutations, rtM204I, was replaced by rtM204V, which also changes the amino acid sequence of the S region (sI195M).
|
|
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HBV Mutation Detail Information