|
Mutation Information
|
Mutation Site
|
I208T |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
S |
|
Amino acid_Mutation
|
T777C |
|
Genotype/Subtype
|
A |
|
Country
|
France |
Literature Information
|
PubMed PMID
|
15016847
|
|
Disease
|
HBV infection
|
|
Published Year
|
2004 |
|
Journal
|
Journal of virology |
|
Title
|
Modulation of hepatitis B virus secretion by naturally occurring mutations in the S gene. |
|
Author
|
Khan N,Guarnieri M,Ahn SH,Li J,Zhou Y,Bang G,Kim KH,Wands JR,Tong S |
|
Evidence
|
However, 3.4 contained substitutions in the S domain (F8L, G119E, and I208T; Fig. Fig.6)6) owing to the T176C, G510A, and T777C mutations in the viral genome (Table,2), which might account for the impairment of virion secretion.
|
|
|
HBV Mutation Detail Information