HBV Mutation Detail Information

> I233V Search Result

Mutation Information

Mutation Site	I233V
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT
Relevant Drug	adefovir (ADV)
Country	Brazil

Literature Information

PubMed PMID	22012717
Disease	Hepatocellular carcinoma
Published Year	2011
Journal	Journal of medical virology
Title	Clonal analysis of hepatitis B viruses among blood donors from Joinville, Brazil: evidence of dual infections, intragenotype recombination and markers of risk for hepatocellular carcinoma.
Author	Reis LM,Soares MA,França PH,Soares EA,Bonvicino CR
Evidence	Three isolates (HBV37, HBV40, and HBV48) showed mutation I233V, whose resistance to adefovir is controversial [Schildgen et al., 2006; Curtis et al., 2007], a reason why this mutation is not included currently in HBV genotyping algorithms.

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation