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Mutation Information
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Mutation Site
|
I309R |
|
Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
Gp41 |
Literature Information
|
PubMed PMID
|
21356539
|
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Published Year
|
2011 |
|
Journal
|
Virology |
|
Title
|
Resistance of a human immunodeficiency virus type 1 isolate to a small molecule CCR5 inhibitor can involve sequence changes in both gp120 and gp41. |
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Author
|
Anastassopoulou CG,Ketas TJ,Depetris RS,Thomas AM,Klasse PJ,Moore JP |
|
Evidence
|
Other changes were also evident at V3 positions adjacent to the first two established resistance-associated substitutions, although only the second of those changes (I309R) had become stabilized by passage 19.
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HIV Mutation Detail Information