|
Mutation Information
|
Mutation Site
|
I326Y |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
Env |
|
Viral Reference
|
K03455.1
|
|
Immune Escape
|
Y |
Literature Information
|
PubMed PMID
|
30709739
|
|
Published Year
|
2019 |
|
Journal
|
Immunity |
|
Title
|
An Antigenic Atlas of HIV-1 Escape from Broadly Neutralizing Antibodies Distinguishes Functional and Structural Epitopes. |
|
Author
|
Dingens AS,Arenz D,Weight H,Overbaugh J,Bloom JD |
|
Evidence
|
We validated that I326Y results in escape from VRC01 (Figure S3), but has little effect on the V3-specific bnAbs 10-1074 and PGT121, despite these antibodies directly contacting this site.
|
|
|
HIV Mutation Detail Information