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Mutation Information
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Mutation Site
|
I50V |
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Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
PR |
Literature Information
|
PubMed PMID
|
33503916
|
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Published Year
|
2021 |
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Journal
|
Molecules (Basel, Switzerland) |
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Title
|
Structural Impacts of Drug-Resistance Mutations Appearing in HIV-2 Protease. |
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Author
|
Laville P,Petitjean M,Regad L |
|
Evidence
|
For example, the I50V mutation caused structural changes in two atoms of residue 50 of the two chains, a residue involved in the binding pocket, the dimer interface and the flap region (Figure 4).
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