|
Mutation Information
|
Mutation Site
|
I54L |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
PR |
|
Relevant Drug
|
PIs;lopinavir (LPV);ritonavir |
|
Country
|
China |
Literature Information
|
PubMed PMID
|
32183889
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2020 |
|
Journal
|
Virology journal |
|
Title
|
Prevalence of acquired drug resistance mutations in antiretroviral- experiencing subjects from 2012 to 2017 in Hunan Province of central South China. |
|
Author
|
Zou X,He J,Zheng J,Malmgren R,Li W,Wei X,Zhang G,Chen X |
|
Evidence
|
Dual-class mutations were observed in 591 (64.66%) cases, and triple-class mutations were observed in 43 (4.70%) cases. M184V (62.04%), K103N (41.90%) and I54L (3.83%) were the most common observed mutations, respectively, in NRTI-, NNRTI- and PI-associated drug resistance.
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HIV Mutation Detail Information