|
Mutation Information
|
Mutation Site
|
I54S |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
PR |
|
Genotype/Subtype
|
CRF01 AE |
|
Relevant Drug
|
PIs |
|
Country
|
Kenya |
Literature Information
|
PubMed PMID
|
30759103
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2019 |
|
Journal
|
PloS one |
|
Title
|
Presence, persistence and effects of pre-treatment HIV-1 drug resistance variants detected using next generation sequencing: A Retrospective longitudinal study from rural coastal Kenya. |
|
Author
|
Hassan AS,Bibby DF,Mwaringa SM,Agutu CA,Ndirangu KK,Sanders EJ,Cane PA,Mbisa JL,Berkley JA |
|
Evidence
|
The third participant had no detectable low frequency variant at the first time-point but developed a PI mutation (I54S [3.6%]) at the second time-point (duration, 11.2 months).
|
|
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HIV Mutation Detail Information