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Mutation Information
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Mutation Site
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I54V |
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Mutation Type
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Amino acid level |
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Gene/Protein/Region Type
|
PR |
Literature Information
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PubMed PMID
|
32478251
|
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Published Year
|
2020 |
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Journal
|
ACS omega |
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Title
|
Visualizing Tetrahedral Oxyanion Bound in HIV-1 Protease Using Neutrons: Implications for the Catalytic Mechanism and Drug Design. |
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Author
|
Kumar M,Mandal K,Blakeley MP,Wymore T,Kent SBH,Louis JM,Das A,Kovalevsky A |
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Evidence
|
The fourth structure (PDB ID 3B80) is of PR i54v mutant variant in which the tetrahedral intermediate has one orientation with 60% occupancy.
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HIV Mutation Detail Information