|
Mutation Information
|
Mutation Site
|
I55N |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
Rev |
Literature Information
|
PubMed PMID
|
28153748
|
|
Published Year
|
2017 |
|
Journal
|
Journal of molecular biology |
|
Title
|
A DEAD-Box Helicase Mediates an RNA Structural Transition in the HIV-1 Rev Response Element. |
|
Author
|
Hammond JA,Lamichhane R,Millar DP,Williamson JR |
|
Evidence
|
The Rev V16D/I55N mutant is oligomerization-deficient, and has a monomeric binding profile in single molecule fluorescence Rev oligomerization assays.
|
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