HBV Mutation Detail Information

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Mutation Information

Mutation Site	I84M
Mutation Type	Amino acid level
Gene/Protein/Region Type	PreS1
Genotype/Subtype	C

Literature Information

PubMed PMID	33803998
Published Year	2021
Journal	Microorganisms
Title	rt269I Type of Hepatitis B Virus (HBV) Polymerase versus rt269L Is More Prone to Mutations within HBV Genome in Chronic Patients Infected with Genotype C2: Evidence from Analysis of Full HBV Genotype C2 Genome.
Author	Jeong H,Kim DH,Choi YM,Choi H,Kim D,Kim BJ
Evidence	We found a total of five types of signature NS mutations in the S ORF (I84T/M/L/V and A90T/V in PreS1, F141L in PreS2, and I68T and L213I/S in S). Of these, the frequency in all four types but one rt269L signature type (I68T in the S region) was significantly or tended to be higher in rt269I HBV strains than in rt269L.

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation