|
Mutation Information
|
Mutation Site
|
I84V |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
PR |
|
Combined Mutation
|
pr.L90M+pr.I84V |
Literature Information
|
PubMed PMID
|
33503916
|
|
Published Year
|
2021 |
|
Journal
|
Molecules (Basel, Switzerland) |
|
Title
|
Structural Impacts of Drug-Resistance Mutations Appearing in HIV-2 Protease. |
|
Author
|
Laville P,Petitjean M,Regad L |
|
Evidence
|
The I50L and I82F mutations were also responsible of an increase of the pocket volume, in contrast to the I82M and I84V mutations that caused a reduction of the pocket volume.
|
|
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HIV Mutation Detail Information