|
Mutation Information
|
Mutation Site
|
I97L |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
C |
|
Country
|
Taiwan(China) |
Literature Information
|
PubMed PMID
|
16227269
|
|
Clinical information
|
Yes
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2005 |
|
Journal
|
Journal of virology |
|
Title
|
Reduced secretion of virions and hepatitis B virus (HBV) surface antigen of a naturally occurring HBV variant correlates with the accumulation of the small S envelope protein in the endoplasmic reticulum and Golgi apparatus. |
|
Author
|
Chua PK,Wang RY,Lin MH,Masuda T,Suk FM,Shih C |
|
Evidence
|
Presence of a core I97L mutation is not sufficient for immature secretion in vivo.
|
|
|
HBV Mutation Detail Information