HIV Mutation Detail Information

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Mutation Information

Mutation Site	K101H
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT
Relevant Drug	NNRTIs
Country	South Africa

Literature Information

PubMed PMID	32071061
Disease	HIV infection/AIDS
Published Year	2020
Journal	Antimicrobial agents and chemotherapy
Title	Discordance between Etravirine Phenotype and Genotype-Based Predicted Phenotype for Subtype C HIV-1 from First-Line Antiretroviral Therapy Failures in South Africa.
Author	McCormick KD,Penrose KJ,Brumme CJ,Harrigan PR,Viana RV,Mellors JW,Parikh UM,Wallis CL
Evidence	No other NNRTI mutations in this sample set, including A98G, K101E/H/P, V106I, E138A/G/K/Q, V179F/T, Y181V or G190S/A were associated with ETR resistance (Table 1).

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation