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HIV Mutation Detail Information

> K103N Search Result


Mutation Information
Mutation Site K103N
Mutation Type Amino acid level
Gene/Protein/Region Type RT
Literature Information
PubMed PMID 32082978
Published Year 2020
Journal Acta pharmaceutica Sinica. B
Title Improving the positional adaptability: structure-based design of biphenyl-substituted diaryltriazines as novel non-nucleoside HIV-1 reverse transcriptase inhibitors.
Author Jin K,Liu M,Zhuang C,De Clercq E,Pannecouque C,Meng G,Chen F
Evidence The modifications commonly introduced some N-containing heterocycles, including both hydrogen-bond donors and acceptors, could increase the interactions with the possible mutants, such as K103N and E138K.
Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation