|
Mutation Information
|
Mutation Site
|
K123E |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Genotype/Subtype
|
B |
|
Viral Reference
|
K03455.1
|
|
Immune Escape
|
Y |
|
Country
|
Canada |
Literature Information
|
PubMed PMID
|
30048246
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2018 |
|
Journal
|
AIDS (London, England) |
|
Title
|
Extensive host immune adaptation in a concentrated North American HIV epidemic. |
|
Author
|
Brumme ZL,Kinloch NN,Sanche S,Wong A,Martin E,Cobarrubias KD,Sandstrom P,Levett PN,Harrigan PR,Joy JB |
|
Evidence
|
The latter included RT-K123E (adapted to B*35 : 01), RT-I135T (B*51 : 01), RT-S162C (B*07 : 02/05), RT-Q207E (B*15 : 01), RT-C297A (B*35 : 03), RT-V317A (B*15 : 01) and RT-E399D (A*32 : 01) (all P <= 0.05).
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HIV Mutation Detail Information