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Mutation Information
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Mutation Site
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K155M |
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Mutation Type
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Amino acid level |
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Gene/Protein/Region Type
|
Env |
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Viral Reference
|
K03455.1
|
Literature Information
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PubMed PMID
|
32192810
|
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Published Year
|
2020 |
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Journal
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Vaccine |
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Title
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Induction of cross-reactive HIV-1 specific antibody responses by engineered V1V2 immunogens with reduced conformational plasticity. |
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Author
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Lai JI,Eszterhas SK,Brooks SA,Guo C,Zolla-Pazner S,Seaman MS,Bailey-Kellogg C,Griswold KE,Ackerman ME |
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Evidence
|
Previously, we identified a V1V2 sequence variant (K155M) that results in enhanced recognition by cross-reactive antibodies recognizing the beta-strand conformation.
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HIV Mutation Detail Information