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Mutation Information
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Mutation Site
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K160T |
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Mutation Type
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Amino acid level |
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Gene/Protein/Region Type
|
IN |
Literature Information
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PubMed PMID
|
18687142
|
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Published Year
|
2008 |
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Journal
|
Retrovirology |
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Title
|
Natural variation of HIV-1 group M integrase: implications for a new class of antiretroviral inhibitors. |
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Author
|
Rhee SY,Liu TF,Kiuchi M,Zioni R,Gifford RJ,Holmes SP,Shafer RW |
|
Evidence
|
E157Q, which decreases raltegravir and elvitegravir susceptibility, was associated with K160Q/T in subtypes A, B, C, and CRF02 and with K156N in three unrelated subtype D isolates.
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