Home
Virus
Gene
Disease
Dataset
Download
Help
 
HIV Mutation Detail Information

> K203A Search Result


Mutation Information
Mutation Site K203A
Mutation Type Amino acid level
Gene/Protein/Region Type CA
Literature Information
PubMed PMID 33332391
Published Year 2020
Journal PLoS biology
Title Permeability of the HIV-1 capsid to metabolites modulates viral DNA synthesis.
Author Xu C,Fischer DK,Rankovic S,Li W,Dick RA,Runge B,Zadorozhnyi R,Ahn J,Aiken C,Polenova T,Engelman AN,Ambrose Z,Rousso I,Perilla JR
Evidence Retention of a higher number of CA puncta per IN particles is indicative of a more stable capsid, which was confirmed by comparing WT HIV-1 to viruses with previously characterized hyperstable E45A CA and hypostable K203A CA amino acid substitutions (S9B and S9C Fig).
Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation