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Mutation Information
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Mutation Site
|
K227R |
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Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
DNase |
Literature Information
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PubMed PMID
|
12604820
|
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Published Year
|
2003 |
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Journal
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The Journal of general virology |
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Title
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Site-directed mutagenesis in a conserved motif of Epstein-Barr virus DNase that is homologous to the catalytic centre of type II restriction endonucleases. |
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Author
|
Liu MT,Hu HP,Hsu TY,Chen JY |
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Evidence
|
However, K227 mutants were found to have variable DNA-binding abilities: K227G and K227N mutants retained, K227E and K227D had reduced and K227R lost DNA-binding ability.
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EBV Mutation Detail Information