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Mutation Information
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Mutation Site
|
K241R |
|
Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
RT |
|
Viral Reference
|
U95551
|
Literature Information
|
PubMed PMID
|
23261845
|
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Published Year
|
2013 |
|
Journal
|
Antiviral research |
|
Title
|
The amino acid substitutions rtP177G and rtF249A in the reverse transcriptase domain of hepatitis B virus polymerase reduce the susceptibility to tenofovir. |
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Author
|
Qin B,Budeus B,Cao L,Wu C,Wang Y,Zhang X,Rayner S,Hoffmann D,Lu M,Chen X |
|
Evidence
|
The remaining 7 aa substitutions, rtL82V, rtD83E, rtN238R, rtT240Y, rtK241R, rtN248H, and rtQ267K, had no obvious effect on HBV replication capacity.
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HBV Mutation Detail Information