HIV Mutation Detail Information

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Mutation Information
Mutation Site K258A
Mutation Type Amino acid level
Gene/Protein/Region Type IN
Literature Information
PubMed PMID 32960169
Published Year 2020
Journal eLife
Title Integrase-RNA interactions underscore the critical role of integrase in HIV-1 virion morphogenesis.
Author Elliott JL,Eschbach JE,Koneru PC,Li W,Puray-Chavez M,Townsend D,Lawson DQ,Engelman AN,Kvaratskhelia M,Kutluay SB
Evidence To corroborate these findings, we analyzed the oligomeric states of recombinant WT, K34A, E96A, V165A, K188E, R199A, Q214L/Q216L, K236E, K258A, and R262A/R263A IN proteins by SEC (Figure 4B).

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation