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Mutation Information
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Mutation Site
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K258A |
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Mutation Type
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Amino acid level |
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Gene/Protein/Region Type
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IN |
Literature Information
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PubMed PMID
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32960169
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Published Year
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2020 |
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Journal
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eLife |
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Title
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Integrase-RNA interactions underscore the critical role of integrase in HIV-1 virion morphogenesis. |
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Author
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Elliott JL,Eschbach JE,Koneru PC,Li W,Puray-Chavez M,Townsend D,Lawson DQ,Engelman AN,Kvaratskhelia M,Kutluay SB |
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Evidence
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To corroborate these findings, we analyzed the oligomeric states of recombinant WT, K34A, E96A, V165A, K188E, R199A, Q214L/Q216L, K236E, K258A, and R262A/R263A IN proteins by SEC (Figure 4B).
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