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Mutation Information
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Mutation Site
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K285I |
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Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
S |
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Viral Reference
|
AF282918.1
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Literature Information
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PubMed PMID
|
19812261
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Published Year
|
2010 |
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Journal
|
The Journal of general virology |
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Title
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Biological significance of amino acid substitutions in hepatitis B surface antigen (HBsAg) for glycosylation, secretion, antigenicity and immunogenicity of HBsAg and hepatitis B virus replication. |
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Author
|
Wu C,Zhang X,Tian Y,Song J,Yang D,Roggendorf M,Lu M,Chen X |
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Evidence
|
The substitutions K122I, T123N and K160N in S-HBsAg in the present study led to the substitutions rtQ476H, rtN477K and rtI515L in HBV polymerase, K285I, T286N and K323N in L-HBsAg, and K178I, T179N and K215N in M-HBsAg,
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