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HPV Mutation Detail Information

> K292R Search Result


Mutation Information
Mutation Site K292R
Mutation Type Amino acid level
Gene/Protein/Region Type E2
Genotype/Subtype HPV16
Literature Information
PubMed PMID 18619639
Published Year 2008
Journal Virology
Title Modification of papillomavirus E2 proteins by the small ubiquitin-like modifier family members (SUMOs).
Author Wu YC,Roark AA,Bian XL,Wilson VG
Evidence He expression levels, intracellular localization, and the DNA-binding activity of HPV16 E2 were unchanged by this K292R mutation, suggesting that the transcriptional defect reflects a functional contribution by sumoylation at this residue.
Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation