HIV Mutation Detail Information

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Mutation Information

Literature Information

PubMed PMID	25383358
Published Year	2014
Journal	Molecular therapy. Methods & clinical development
Title	Efficient Transduction of LEDGF/p75 Mutant Cells by Gain-of-Function HIV-1 Integrase Mutant Viruses.
Author	Wang H,Shun MC,Li X,Di Nunzio F,Hare S,Cherepanov P,Engelman A
Evidence	Here we describe the selection and characterization of the K42E gain-of-function mutation in IN, which greatly improves the efficiency of this system.

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Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)