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Mutation Information

Mutation Site	K65E
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT
Relevant Drug	lamivudine (LAM);emtricitabine (FTC)
Country	Madrid

Literature Information

PubMed PMID	33734374
Disease	HIV infection/AIDS
Published Year	2021
Journal	The Journal of antimicrobial chemotherapy
Title	Prevalence of M184V and K65R in proviral DNA from PBMCs in HIV-infected youths with lamivudine/emtricitabine exposure.
Author	Jiménez de Ory S,Beltrán-Pavez C,Gutiérrez-López M,Santos MDM,Prieto L,Sainz T,Guillen S,Aguilera-Alonso D,Díez C,Bernardino JI,Mellado MJ,Ramos JT,Holguín Á,Navarro M
Evidence	Revalence of M184V and K65R in proviral DNA from PBMCs in HIV-infected youths with lamivudine/emtricitabine exposure. OBJECTIVES: We analysed the prevalence of M184V/I and/or K65R/E/N mutations archived in proviral DNA (pDNA) in youths with perinatal HIV, virological control and who previously carried these resistance mutations in historic plasma samples.

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Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation