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HIV Mutation Detail Information

> K65R Search Result


Mutation Information
Mutation Site K65R
Mutation Type Amino acid level
Gene/Protein/Region Type RT
Relevant Drug NRTIs;RT1t49
Literature Information
PubMed PMID 16207371
Published Year 2005
Journal AIDS research and therapy
Title HIV-1 reverse transcriptase mutations that confer decreased in vitro susceptibility to anti-RT DNA aptamer RT1t49 confer cross resistance to other anti-RT aptamers but not to standard RT inhibitors.
Author Fisher TS,Joshi P,Prasad VR
Evidence This result was tempered by the observation that NRTI-resistance mutations such as K65R can confer resistance to some anti-RT aptamers.
Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation