|
Mutation Information
|
Mutation Site
|
K65R |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Genotype/Subtype
|
AE |
|
Viral Reference
|
K03455.1
|
|
Relevant Drug
|
NNRTIs |
|
Country
|
China |
Literature Information
|
PubMed PMID
|
32102660
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2020 |
|
Journal
|
BMC infectious diseases |
|
Title
|
Natural polymorphisms in HIV-1 CRF01_AE strain and profile of acquired drug resistance mutations in a long-term combination treatment cohort in northeastern China. |
|
Author
|
Sun Z,Ouyang J,Zhao B,An M,Wang L,Ding H,Han X |
|
Evidence
|
The mutation rate at 14 sites increased significantly at TF time point compared to baseline, with the most common DRMs comprising G190S/C, K65R, K101E/N/Q, M184 V/I, and V179D/I/A/T/E, ranging from 66.7 to 45.2%.
|
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HIV Mutation Detail Information