|
Mutation Information
|
Mutation Site
|
K70R |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Viral Reference
|
K03455.1
|
|
Relevant Drug
|
NNRTIs |
|
Country
|
Brazil |
Literature Information
|
PubMed PMID
|
33788308
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2021 |
|
Journal
|
Journal of medical virology |
|
Title
|
HIV-1 subtypes and drug resistance in children during antiretroviral therapy in Brazil. |
|
Author
|
de Andrade Arrais CR,Lima K,Barreiros M,Rodrigues JKF,Sousa NPS,Costa DD,Santos FDRP,Pereira GFM,E Silva Viana AI,Barros AK,Leal É |
|
Evidence
|
M184V was the most frequent mutation among NRTIs, found in 39/132 (29.5%) individuals. The most common mutations in NRTIs were M41L (13/132, 9.8%), T215Y (11/132, 8.3%), D67N (10/132, 7.6%), and K70R (8/132, 6.1%), all called analogous thymidine mutations (TAMs), selected for mainly by AZT.
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HIV Mutation Detail Information