HBV Mutation Detail Information

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Mutation Information
Mutation Site L140A
Mutation Type Amino acid level
Gene/Protein/Region Type C
Literature Information
PubMed PMID 33493210
Published Year 2021
Journal PLoS pathogens
Title Multiple roles of PP2A binding motif in hepatitis B virus core linker and PP2A in regulating core phosphorylation state and viral replication.
Author Xi J,Luckenbaugh L,Hu J
Evidence Interestingly, L140A, predicted to impair B56 binding, reduced dephosphorylation at the A701 epitope but dramatically enhanced dephosphorylation at the 25-7 epitope (Fig 2B /lane 4/).

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation