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Mutation Information
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Mutation Site
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L178M |
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Mutation Type
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Amino acid level |
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Gene/Protein/Region Type
|
LMP1 |
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Viral Reference
|
V01555.2
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Country
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Japanese |
Literature Information
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PubMed PMID
|
16917737
|
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Disease
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NK/T cell lymphoma
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Published Year
|
2007 |
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Journal
|
Virus genes |
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Title
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Sequence variations of Epstein-Barr virus LMP1 gene in nasal NK/T-cell lymphoma. |
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Author
|
Nagamine M,Takahara M,Kishibe K,Nagato T,Ishii H,Bandoh N,Ogino T,Harabuchi Y |
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Evidence
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In the epitope WLLLFLAIL (codon 173181), four patients (patient 4, 5, 6 and 7) had amino acid changes Leu to Met at codon 178 and only patient 7 had another amino acid change Leu to Ile at codon 174. Discussion It is very interesting whether EBV-carrying malignan- cies are infected with particularly oncogenic EBV strains.
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EBV Mutation Detail Information