|
Mutation Information
|
Mutation Site
|
L180M |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Combined Mutation
|
rt.M204V+rt.L180M;rt.M204I+rt.L180M |
|
Relevant Drug
|
lamivudine (LAM) |
Literature Information
|
PubMed PMID
|
15655050
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2005 |
|
Journal
|
Journal of viral hepatitis |
|
Title
|
Activity of adefovir dipivoxil against all patterns of lamivudine-resistant hepatitis B viruses in patients. |
|
Author
|
Westland CE,Yang H,Delaney WE 4th,Wulfsohn M,Lama N,Gibbs CS,Miller MD,Fry J,Brosgart CL,Schiff ER,Xiong S |
|
Evidence
|
In addition to the rtM204V/I and the rtL180M mutations, the mutation rtV173L was identified in 19% of patients.
|
|
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HBV Mutation Detail Information