|
Mutation Information
|
Mutation Site
|
L180M |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Combined Mutation
|
rt.M204I+rt.M204V+rt.L180M |
|
Genotype/Subtype
|
A;D;F |
|
Relevant Drug
|
lamivudine (LAM) |
Literature Information
|
PubMed PMID
|
15918335
|
|
Disease
|
HBV infection
|
|
Published Year
|
2005 |
|
Journal
|
Antiviral therapy |
|
Title
|
Evaluation of methods for monitoring drug resistance in chronic hepatitis B patients during lamivudine therapy based on mass spectrometry and reverse hybridization. |
|
Author
|
Kim HS,Han KH,Ahn SH,Kim EO,Chang HY,Moon MS,Chung HJ,Yoo W,Kim SO,Hong SP |
|
Evidence
|
A total of 60 patient samples were analysed for the presence of mutations at rtL1 80M and rtM204I/V of HBV polymerase by the LiPA and RFMP assays.
|
|
|
HBV Mutation Detail Information