|
Mutation Information
|
Mutation Site
|
L180M |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Genotype/Subtype
|
C |
|
Country
|
Korea |
Literature Information
|
PubMed PMID
|
20332649
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2010 |
|
Journal
|
Intervirology |
|
Title
|
Response to adefovir depends on mutation patterns in precore region, basal core promoter and reverse transcriptase, and on-treatment responses in Lamivudine-resistant chronic hepatitis B patients. |
|
Author
|
Song BC,Cui XJ,Shin JW,Park NH,Cho YK,Song HJ,Hyun S,Jeong SU,Choi EK,Kim HU |
|
Evidence
|
There was no difference in virologic response rate according to age, sex, serum ALT level or the pattern of rtM204/ rtL180M mutation.
|
|
|
HBV Mutation Detail Information