|
Mutation Information
|
Mutation Site
|
L180M |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Combined Mutation
|
rt.M204V+rt.L180M |
|
Genotype/Subtype
|
B;C |
|
Viral Reference
|
Y1855;
DQ448619.1 |
|
Relevant Drug
|
lamivudine (LAM) |
|
Country
|
China |
Literature Information
|
PubMed PMID
|
22138714
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2012 |
|
Journal
|
Antiviral research |
|
Title
|
Prevalence, virology and antiviral drugs susceptibility of hepatitis B virus rtN238H polymerase mutation from 1865 Chinese patients with chronic hepatitis B. |
|
Author
|
Zhong Y,Lv J,Li J,Xing X,Zhu H,Su H,Chen L,Zhou X |
|
Evidence
|
These were compared to WT as well as ADV- (rtN236T) and LAM resistant (rtM204I or rtL180M + rtM204V) constructs.
|
|
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HBV Mutation Detail Information