HBV Mutation Detail Information

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Mutation Information

Mutation Site	L180M
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT
Combined Mutation	rt.M204V+rt.L180M
Relevant Drug	lamivudine (LAM);entecavir (ETV);adefovir dipivoxil (ADV);tenofovir (TDF)
Country	United Kingdom

Literature Information

PubMed PMID	22312387
Disease	Chronic hepatitis B
Published Year	2010
Journal	Hepatitis monthly
Title	Multidrug-resistant hepatitis B virus strain in a chronic Turkish patient.
Author	Sayan M,Hulagu S,Karatayli SC
Evidence	In the 18th month of the ETV monotherapy, direct sequencing showed reduced susceptibility to ETV (rtL180M+rtM204V).

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation