|
Mutation Information
|
Mutation Site
|
L180M |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Country
|
USA |
Literature Information
|
PubMed PMID
|
22510694
|
|
Disease
|
HBV infection
|
|
Published Year
|
2012 |
|
Journal
|
Nature communications |
|
Title
|
Convergence and coevolution of hepatitis B virus drug resistance. |
|
Author
|
Thai H,Campo DS,Lara J,Dimitrova Z,Ramachandran S,Xia G,Ganova-Raeva L,Teo CG,Lok A,Khudyakov Y |
|
Evidence
|
Besides the sites for the primary (rtM204V/I) and secondary (rtL180M) lamivudine-resistance mutations identified in five patients, only one additional site with significant changes in intra-host populations was shared by HBV in three patients and four sites by HBV in two patients.
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HBV Mutation Detail Information