|
Mutation Information
|
Mutation Site
|
L180M |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Genotype/Subtype
|
B |
|
Viral Reference
|
AF100309
|
|
Relevant Drug
|
lamivudine (LAM) |
Literature Information
|
PubMed PMID
|
24583110
|
|
Published Year
|
2014 |
|
Journal
|
Journal of virological methods |
|
Title
|
Generation of a human hepatoma cell line supporting efficient replication of a lamivudine resistant hepatitis B virus. |
|
Author
|
Zhang Y,Zhang Y,Kang Y,Wang J,Liu H,Zhu H,Qin Y,Mao R,Lin X,Lu M,Zhang J |
|
Evidence
|
2 unit length of HBV genome harboring rtL180M and rtM204V mutations that confer LAM resistance.
|
|
|
HBV Mutation Detail Information