|
Mutation Information
|
Mutation Site
|
L180M |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Relevant Drug
|
lamivudine (LAM) |
|
Country
|
China |
Literature Information
|
PubMed PMID
|
26505028
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2015 |
|
Journal
|
Journal of nanoscience and nanotechnology |
|
Title
|
A Nanoscale Mutation-Sensitive On/Off Switch Based Assays for the Detection of Hepatitis B Virus Lamivudine-Resistant Mutations. |
|
Author
|
Sun A,Pu W,Zhou C,Zhang R,Liu B,Pan Y,Zhang J,Li P,Lil K |
|
Evidence
|
The purpose of this study was to develop methods for detecting the mutations of YMDD, rtL180M, and rtV173L by nanoscale mutation-sensitive switch consisting of high fidelity polymerase and phosphorothioate-modified allele specific primers.
|
|
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HBV Mutation Detail Information