|
Mutation Information
|
Mutation Site
|
L180M |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Genotype/Subtype
|
A;B;C;D;E;F;G;H;I |
|
Relevant Drug
|
lamivudine (LAM);telbivudine (LDT);entecavir (ETV) |
Literature Information
|
PubMed PMID
|
33238650
|
|
Published Year
|
2020 |
|
Journal
|
Viruses |
|
Title
|
Global Occurrence of Clinically Relevant Hepatitis B Virus Variants as Found by Analysis of Publicly Available Sequencing Data. |
|
Author
|
Velkov S,Protzer U,Michler T |
|
Evidence
|
M204V/I and L180M were the most abundant mutations found that were present in sequences of all genotypes, and they are associated with resistance toward lamivudine, telbivudine, and entecavir.
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HBV Mutation Detail Information