|
Mutation Information
|
Mutation Site
|
L205V |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
S |
|
Genotype/Subtype
|
D |
Literature Information
|
PubMed PMID
|
11481624
|
|
Disease
|
Fulminant hepatitis B
|
|
Published Year
|
2001 |
|
Journal
|
Hepatology (Baltimore, Md.) |
|
Title
|
A dominant hepatitis B virus population defective in virus secretion because of several S-gene mutations from a patient with fulminant hepatitis. |
|
Author
|
Kalinina T,Riu A,Fischer L,Will H,Sterneck M |
|
Evidence
|
The two mutations present at the C-terminal end (S204Rand L205V; construct M8; Fig. 1) of the variant S-proteins alsoled to an approximately 30% reduction of secretion.
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