HBV Mutation Detail Information

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Mutation Information

Mutation Site	L217R
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT
Combined Mutation	rt.L217R+rt.H135T;rt.L217R+rt.L144F;rt.L217R+rt.I163V;rt.L217R+rt.P177R;rt.L217R+rt.L179R;rt.L217R+rt.K212R
Genotype/Subtype	E
Country	Nigeria

Literature Information

PubMed PMID	26148052
Disease	Occult HBV infection; HBV infection
Published Year	2015
Journal	PloS one
Title	Occult Hepatitis B Virus Infection in Nigerian Blood Donors and Hepatitis B Virus Transmission Risks.
Author	Oluyinka OO,Tong HV,Bui Tien S,Fagbami AH,Adekanle O,Ojurongbe O,Bock CT,Kremsner PG,Velavan TP
Evidence	The L217R polymorphism in the reverse transcriptase domain of the HBV polymerase gene was observed significantly higher in OBI compared with HBsAg positive individuals (P<0.0001).

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation