|
Mutation Information
|
Mutation Site
|
L228R |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Genotype/Subtype
|
AE |
|
Viral Reference
|
K03455.1
|
|
Country
|
China |
Literature Information
|
PubMed PMID
|
32102660
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2020 |
|
Journal
|
BMC infectious diseases |
|
Title
|
Natural polymorphisms in HIV-1 CRF01_AE strain and profile of acquired drug resistance mutations in a long-term combination treatment cohort in northeastern China. |
|
Author
|
Sun Z,Ouyang J,Zhao B,An M,Wang L,Ding H,Han X |
|
Evidence
|
Moreover, two unknown mutations (V75 L and L228R) increased by 19.0 and 11.9% respectively, and they were under positive selection (Ka/Ks > 1, log odds ratio [LOD] > 2) and were associated with several other DRMs (cKa/Ks > 1, LOD > 2).
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HIV Mutation Detail Information