|
Mutation Information
|
Mutation Site
|
L229G |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Combined Mutation
|
rt.L229G+s.C221G+s.F220L |
|
Amino acid_Mutation
|
T815G;T814G |
|
Genotype/Subtype
|
D |
|
Relevant Drug
|
lamivudine (LAM) |
|
Country
|
India |
Literature Information
|
PubMed PMID
|
16428891
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2006 |
|
Journal
|
Intervirology |
|
Title
|
Characterization of naturally occurring and Lamivudine-induced surface gene mutants of hepatitis B virus in patients with chronic hepatitis B in India. |
|
Author
|
Kazim SN,Sarin SK,Sharma BC,Khan LA,Hasnain SE |
|
Evidence
|
Mutations at nt. 814 and 815 (TT to GG) were also found in a lamivudine-re-sistant patient affecting both polymerase (rtL229G) and surface genes (sF220L and sC221G; tables 3, 4 ).
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HBV Mutation Detail Information