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Mutation Information
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Mutation Site
|
L234I |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
IN |
|
Viral Reference
|
K03455.1
|
|
Relevant Drug
|
INSTIs |
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Country
|
Russia |
Literature Information
|
PubMed PMID
|
32752001
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2020 |
|
Journal
|
Viruses |
|
Title
|
Genetic Features of HIV-1 Integrase Sub-Subtype A6 Predominant in Russia and Predicted Susceptibility to INSTIs. |
|
Author
|
Kirichenko A,Lapovok I,Baryshev P,van de Vijver DAMC,van Kampen JJA,Boucher CAB,Paraskevis D,Kireev D |
|
Evidence
|
The 9 amino acid substitutions (V31I, T112V, I113V, T125A, G134N, K136Q, D167E, T218I, and L234I) were described as polymorphic mutations in non-B clades, none of which were ascribed to INSTI resistance.
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HIV Mutation Detail Information