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Mutation Information
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Mutation Site
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L320S |
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Mutation Type
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Amino acid level |
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Gene/Protein/Region Type
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Tax |
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Combined Mutation
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tax.L320S+tax.L319R |
Literature Information
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PubMed PMID
|
14645559
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Published Year
|
2003 |
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Journal
|
Journal of virology |
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Title
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The central region of human T-cell leukemia virus type 1 Tax protein contains distinct domains involved in subunit dimerization. |
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Author
|
Basbous J,Bazarbachi A,Granier C,Devaux C,Mesnard JM |
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Evidence
|
As a negative control, we tested M47 (L319R and L320S), that is also inhibited in transactivation of the HTLV-1 promoter. Each mutant was fused to the GAL4 activation domain and tested in yeast for interaction with WT Tax (Fig. (Fig.6).6).
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HTLV1 Mutation Detail Information