HBV Mutation Detail Information

> L515M Search Result

Mutation Information

Mutation Site	L515M
Mutation Type	Amino acid level
Gene/Protein/Region Type	P
Relevant Drug	lamivudine (LAM)

Literature Information

PubMed PMID	33364535
Published Year	2020
Journal	AIMS microbiology
Title	Mutations and methods of analysis of mutations in Hepatitis B virus.
Author	Rajput MK
Evidence	The viremia reaches on average 10% of the pretreatment level after cessation of lamivudine treatment Point mutations Phe-501 to Leu 515 to Met Found in lamivudine treated patients pre-S1 Mutation in epitopes located at aa 10 to 48 or 58 to 100 May affect viral clearance from the host Deletions in the central part of pre-S1 and extended into the 3'part.

Contents
Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation