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HBV Mutation Detail Information

> L528M Search Result


Mutation Information
Mutation Site L528M
Mutation Type Amino acid level
Gene/Protein/Region Type P
Combined Mutation p.M552I+p.L528M
Genotype/Subtype D
Relevant Drug lamivudine (LAM)
Country Japan
Literature Information
PubMed PMID 11181644
Published Year 2001
Journal The Journal of clinical investigation
Title The polymerase L528M mutation cooperates with nucleotide binding-site mutations, increasing hepatitis B virus replication and drug resistance.
Author Ono SK,Kato N,Shiratori Y,Kato J,Goto T,Schinazi RF,Carrilho FJ,Omata M
Evidence The polymerase L528M mutation cooperates with nucleotide binding-site mutations, increasing hepatitis B virus replication and drug resistance.
Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation