|
Mutation Information
|
Mutation Site
|
L528M |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
P |
|
Combined Mutation
|
p.M552I+p.L528M |
|
Relevant Drug
|
lamivudine (LAM) |
Literature Information
|
PubMed PMID
|
11397661
|
|
Published Year
|
2001 |
|
Journal
|
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology |
|
Title
|
Detection of hepatitis B virus resistance to antivirals. |
|
Author
|
Zoulim F |
|
Evidence
|
The lamivudine resistant mutants, selected in vivo, can be classified in 2 main groups: group I with a double mutation L528M and M552V, and group II with a single mutation M5521.
|
|
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HBV Mutation Detail Information