HBV Mutation Detail Information

> L528M Search Result

Mutation Information

Mutation Site	L528M
Mutation Type	Amino acid level
Gene/Protein/Region Type	P
Genotype/Subtype	C
Immune Escape	Y
Relevant Drug	lamivudine (LAM)

Literature Information

PubMed PMID	14981758
Disease	HBV infection
Published Year	2004
Journal	Journal of medical virology
Title	Identification of rare polymerase variants of hepatitis B virus using a two-stage PCR with peptide nucleic acid clamping.
Author	Ohishi W,Shirakawa H,Kawakami Y,Kimura S,Kamiyasu M,Tazuma S,Nakanishi T,Chayama K
Evidence	This variant did not have the L528M mutation, which is often associated with YVDD variants, and lamivudine therapy in this patient suppressed HBV replication.

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation